The Future of Hepatitis D: Insights on the 2025 Phase 3 Trial Launch

Navigating the Landscape of Hepatitis D: Your Guide to 2025's Phase 3 Trial
You must have often heard about hepatitis D virus, right? Hepatitis D virus is a deadly virus just like hepatitis B. It can only infect hepatitis B patients, not any normal person. Because, hepatitis D or Delta Virus can survive and grow only with hepatitis B virus. Treatment for hepatitis delta virus is not properly available worldwide at the moment. Treatment options are limited in the US and European countries. However, people suffering from both hepatitis B and D viruses have a higher risk of irreversible liver damage and life-threatening complications.

The condition of a co-infected patient can be even worse. There is good news about the treatment of hepatitis D. Vir Biotechnology is advancing its combination treatment in hepatitis B and D, but it is pausing further development in hepatitis B while it is looking for a suitable partner.

In 2024, Vir arrived at a liver disease conference with data from a Phase 2 trial showing that two combination regimens using its drugs for bevibart and alebsiran were able to reduce hepatitis B surface antigens. The company planned to continue the trial up to the 24-week stage to evaluate whether its cocktail therapy could serve as a functional cure for chronic hepatitis B patients. According to the biotech's fourth-quarter earnings release, Vir Biotechnology still expects this data in the second quarter of the year.

I think this is a great news; it's time to congratulate! Best wishes to Vir Biotechnology for moving forward without delay. He then added, We are poised for significant progress with the start of our Phase 3 registration program in chronic hepatitis delta and further clinical progress of our dual-masked T-cell engagers in solid tumours. Please watch full video to know more about the details.

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